RegulonDB evolutionary first Genes of Regulon

Summary of evolutionary conservation promoters regulated by PhoB

The evolutionary conservation of promoters is limited to Gammaproteobacteria and to sigma70 promoters. In general an promoter is conserved if, i) the position of the promoter from the gene start is conserved, or ii) the promoter sequence recognized by the sigma70 factor is conserved (p < 0.0001). To avoid redundancy, the orthologous regions were purged using the program Purge-Sequence from RSAtools. Orthologs consisted of BLAST reciprocal best hits using soft masking and Smith-Waterman alignments.

First gene Promoter name Evolutionary conservation ratio (nd) Footprint conservation
adiC adiCp7 (nd)
amn amnp1 (nd)
argP argPp (nd)
asr asrp (nd)
cra fruRp8 (nd)
cusC cusCp 0.01
cusR cusRp 0.12
eda edap1 (nd)
edap2 (nd)
edap3 (nd)
eddp1 0.02
feaR feaRp (nd)
feaRp1 (nd)
feaRp2 (nd)
feaRp3 (nd)
gadX gadAp (nd)
gadXp (nd)
gadXp (nd)
gadX gadAp (nd)
gadXp (nd)
gadXp (nd)
hiuH hiuHp (nd)
mipA mipAp (nd)
ompF ompFp (nd)
phnC phnCp (nd)
phoA phoAp (nd)
phoB phoBp 0.10
phoE phoEp (nd)
phoH phoHp1 (nd)
phoHp2 (nd)
phoQ phoPp1 (nd)
phoPp2 (nd)
phoPp3 (nd)
phoQp5 (nd)
phoU phoUp 0.01
pstBp 0.01
pstBp1 0.01
pstCp 0.01
pstSp 0.02
pitB pitBp 0.06
prpR prpRp (nd)
psiE psiEp 0.05
pstS pstSp 0.02
pstSp 0.02
pstSp 0.02
pstS pstSp 0.02
pstSp 0.02
pstSp 0.02
pstS pstSp 0.02
pstSp 0.02
pstSp 0.02
sbcD sbcDp 0.06
tktB talAp1 (nd)
talAp2 (nd)
tktBp (nd)
ugpB ugpBp1 0.34
ugpBp2 0.03
ugpB ugpBp1 0.34
ugpBp2 0.03
ydfH ydfHp (nd)
yegH yegHp (nd)
yhjC yhjCp (nd)
waaH yibDp1 0.17
ytfK ytfKp (nd)